Here’s a statistic that should make you reconsider your next meal: approximately 40% of Singapore’s population has non-alcoholic fatty liver disease (NAFLD)—significantly above the global average of 5-18%. Indeed, that means 2 out of every 5 Singaporeans you pass on the street likely have fat accumulating in their liver, most without any symptoms whatsoever.

Furthermore, according to Singapore’s Burden of Disease Survey, liver cancer ranks as the 5th most common cancer in males, while liver cirrhosis contributes to nearly 1% of all years of life lost. Moreover, chronic hepatitis B causes 63.3% of liver cirrhosis cases in Singapore, despite our universal vaccination program. Consequently, liver disease remains a critical public health concern.

The truly concerning part? While 91.2% of Singaporeans agree that regular liver screening is important, only 65.4% actually attended health screening within the past two years. Additionally, awareness of specific liver diagnostic tests remains shockingly low—only about 20% of people correctly identify what tests actually assess liver health. Therefore, this knowledge gap puts many at risk.

Therefore, liver health screening Singapore medical centers like HOP Medical Centre offer provides the early detection necessary to prevent liver disease progression before symptoms appear. In most cases, early-stage fatty liver disease is completely reversible through lifestyle changes—but only if you know you have it. Consequently, understanding what these screenings involve and when you need them could literally save your liver and your life.

Book Your Liver Health Screening at HOP

The Silent Nature of Liver Disease: Why Screening Matters

Your liver is remarkably resilient and can continue functioning even when significantly damaged. Indeed, this resilience becomes dangerous because liver disease typically progresses silently—you feel perfectly fine while irreversible scarring quietly destroys your liver. Consequently, regular screening becomes your only defense.

Singapore’s Growing Liver Disease Crisis

The liver disease burden in Singapore is projected to rise from 1,492,000 cases in 2019 to 1,799,000 by 2030. Furthermore, this represents an alarming increase driven primarily by the meteoric rise in fatty liver disease linked to obesity, diabetes, and metabolic syndrome. Therefore, early intervention has never been more critical.

According to research on liver disease in Singapore, fatty liver prevalence has increased significantly over the past decade. Specifically, in one study of patients undergoing cholecystectomy, fatty liver prevalence jumped from 40% to 56.6% over just a 10-year period. Moreover, nearly 10% of all liver transplants in Singapore are now NAFLD-related—a percentage that continues to climb. Consequently, fatty liver disease is becoming Singapore’s silent epidemic.

The Hidden Danger of Asymptomatic Disease

Unlike other organs that signal distress through pain or dysfunction, your liver suffers in silence. Therefore, people with early-stage fatty liver, alcoholic liver disease, or even chronic hepatitis often experience no symptoms whatsoever until the damage becomes severe. Indeed, this makes screening absolutely essential.

By the time symptoms like jaundice (yellowing of skin/eyes), abdominal swelling, confusion, or bleeding problems appear, liver disease has often progressed to cirrhosis—irreversible scarring that can only be managed, not cured. Consequently, waiting for symptoms means waiting until it’s too late for reversal. Moreover, at this stage, treatment options become limited.

Early Detection Through Screening

Liver health screening Singapore clinics provide identifies problems when intervention can still make a difference. Additionally, regular screening can detect:

• Elevated liver enzymes (ALT, AST, GGT, ALP) indicating liver inflammation or damage
• Fatty liver disease before progression to cirrhosis
• Viral hepatitis B or C that requires treatment
• Low albumin levels suggesting impaired liver function
• High bilirubin indicating bile flow problems or liver dysfunction
• Metabolic risk factors like diabetes and high cholesterol that harm your liver

By detecting these issues early, healthcare providers can implement interventions—whether lifestyle modifications, antiviral medications for hepatitis, alcohol cessation support, or specific liver-protective treatments—that can halt or even reverse liver damage. Furthermore, at HOP Medical Centre, our comprehensive liver health screening packages are specifically designed to catch these silent threats when treatment is most effective. Therefore, investing in regular screening protects your long-term liver health.

Understanding Your Liver Disease Risk Factors

Not everyone faces the same liver disease risk. Indeed, several factors, both modifiable and non-modifiable, influence whether you should prioritize liver health screening Singapore medical centers offer.

Non-Modifiable Risk Factors

Age: Liver disease risk increases with age, particularly after 50. Moreover, chronic hepatitis B—Singapore’s leading cause of liver cirrhosis—predominantly affects older generations who weren’t vaccinated in childhood. Consequently, age-appropriate screening becomes increasingly important.

Ethnicity and Genetics: Certain genetic factors influence liver disease susceptibility. Furthermore, Asian populations show higher rates of hepatitis B carrier states and may metabolize alcohol differently than other ethnic groups. Therefore, ethnicity affects screening recommendations.

Family History: If close relatives developed liver cancer, cirrhosis, or chronic hepatitis, your risk increases substantially. Additionally, some liver conditions like Wilson’s disease and hemochromatosis run in families. Consequently, knowing your family history is crucial for risk assessment.

Gender: Men face higher liver cancer risk, with liver cancer being the 5th most common male cancer in Singapore. Specifically, the age-adjusted rate is 17.6 per 100,000 population for males. Moreover, gender differences in liver disease progression warrant consideration in screening protocols.

Modifiable Risk Factors

Metabolic and Dietary Factors

Obesity and Metabolic Syndrome: These are the primary drivers of Singapore’s fatty liver epidemic. Indeed, with obesity affecting approximately 11% of Singaporeans and diabetes affecting another 11%, metabolic-related liver disease continues surging. Moreover, even people with “normal” BMI can develop fatty liver if they carry excess abdominal fat or have metabolic abnormalities.

Diabetes: Diabetics face significantly elevated fatty liver risk. Furthermore, research shows diabetics have a hazard ratio of 2.14 for developing liver cancer (hepatocellular carcinoma), even independent of viral hepatitis markers. Therefore, all diabetic patients should undergo regular liver health screening.

High Cholesterol and Triglycerides: Dyslipidemia affects 17.4% of Singaporeans according to national health surveys. Additionally, elevated blood fats contribute directly to fatty liver development and progression. Therefore, managing lipid levels is essential for liver health.

Poor Diet: Singapore’s food culture, while delicious, often includes high sugar content (bubble tea, kaya toast), excessive carbohydrates (white rice, noodles), and fried foods—all contributing to fatty liver development. Moreover, the convenience of hawker centers makes unhealthy eating patterns easy to maintain.

Alcohol and Infectious Causes

Alcohol Consumption: Singapore data shows alcohol causes 11.2% of liver cirrhosis cases. However, even moderate drinking can cause liver damage in susceptible individuals. Additionally, binge drinking—increasingly common in Singapore’s social culture—can rapidly lead to alcoholic liver disease. Consequently, any regular alcohol consumption warrants monitoring.

Viral Hepatitis B: With an overall seroprevalence rate of 3.6% in Singapore, hepatitis B remains a major liver disease driver. Moreover, chronic hepatitis B causes 63.3% of liver cirrhosis cases. Consequently, all Singaporeans should know their hepatitis B status through liver health screening.

Viral Hepatitis C: Though less common (approximately 0.1% prevalence), hepatitis C causes significant complications and is a common indication for liver transplants in Singapore. Furthermore, many people contracted hepatitis C years ago without knowing it, as the virus can remain dormant for decades.

Medication and Drug-Related Factors

Certain Medications: Long-term use of some medications—including certain antibiotics, NSAIDs, methotrexate, and some traditional/herbal remedies—can cause liver damage. Therefore, regular liver monitoring is essential for people on long-term medication regimens.

Taking Control of Your Liver Health

If you have multiple risk factors, your need for liver health screening Singapore medical facilities provide becomes increasingly urgent. Nevertheless, HOP Medical Centre offers tailored screening packages designed to assess your specific risk profile, from our Express Health Screening for time-conscious professionals to comprehensive Executive Health Screening packages that include detailed liver function assessment.

Explore HOP’s Executive Health Screening Packages

Liver Health Screening Tests at HOP Medical Centre

At HOP Medical Centre, we provide comprehensive liver function screening through our in-house diagnostic capabilities. Understanding these tests helps you know what to expect during your liver health screening Singapore visit. Moreover, knowing what each test measures empowers you to better understand your results.

Blood Tests for Liver Function

Alanine Aminotransferase (ALT/SGPT)

This enzyme resides primarily in liver cells. Specifically, when liver cells are damaged, ALT leaks into your bloodstream. Therefore, elevated ALT levels indicate liver inflammation or injury. Consequently, ALT is one of the first indicators doctors check for liver problems.

Normal ALT levels:

• Men: 7-55 units per liter (U/L)
• Women: 7-45 U/L

Furthermore, ALT is considered the most specific liver enzyme, as it’s found predominantly in the liver rather than other organs. Additionally, even mild elevations can signal early liver disease that requires attention.

Aspartate Aminotransferase (AST/SGOT)

AST is found in liver cells but also in heart muscle, skeletal muscles, kidneys, and other organs. Moreover, elevated AST levels can indicate liver damage, though they’re less specific than ALT. Therefore, doctors always interpret AST alongside ALT for accurate assessment.

Normal AST levels: 8-48 U/L

Additionally, the AST/ALT ratio helps doctors determine the cause of liver disease. Specifically, an AST/ALT ratio greater than 2:1 often suggests alcoholic liver disease. Consequently, this ratio provides valuable diagnostic clues.

Cholestatic Liver Enzymes

Alkaline Phosphatase (ALP)

This enzyme is concentrated in liver bile ducts, bones, and a few other tissues. Therefore, elevated ALP suggests bile duct problems or cholestatic (bile flow) liver disease. However, it can also indicate bone disease, which is why additional testing is important.

Normal ALP levels: 44-147 U/L (varies by lab)

Consequently, when ALP is elevated alongside GGT, it strongly indicates the liver rather than bones as the source of elevation. Moreover, this combination helps pinpoint bile duct issues specifically.

Gamma-Glutamyl Transferase (GGT)

GGT is an enzyme found primarily in liver and bile ducts. Furthermore, it’s particularly sensitive to alcohol-related liver damage and bile duct problems. Therefore, GGT elevation often appears before other liver enzymes rise.

Normal GGT levels:

• Men: 8-61 U/L
• Women: 5-36 U/L

Moreover, elevated GGT combined with elevated ALP confirms liver/bile duct origin rather than bone disease. Additionally, GGT elevation is one of the earliest signs of alcohol-related liver damage. Consequently, this test is especially valuable for detecting early-stage liver problems.

Liver Synthetic Function Tests

Albumin

Your liver produces albumin, the main protein in blood plasma. Therefore, albumin levels directly reflect your liver’s synthetic capability. Consequently, monitoring albumin helps assess how well your liver is functioning overall.

Normal albumin levels: 3.5-5.5 g/dL

Furthermore, low albumin indicates chronic liver disease where the liver can no longer produce adequate protein. Additionally, albumin helps maintain blood volume and transports hormones, vitamins, and medications throughout your body. Moreover, severely low albumin (below 2.5 g/dL) signals advanced liver dysfunction requiring immediate attention.

Total Protein

This measures all proteins in blood, including albumin and globulins. Consequently, the total protein test provides a broader picture of liver function and nutritional status. Therefore, it complements the albumin test for comprehensive assessment.

Normal total protein: 6.0-8.3 g/dL

Moreover, the albumin/globulin (A/G) ratio helps identify specific liver conditions—low ratios can indicate cirrhosis, while high ratios might suggest certain genetic disorders or leukemia. Additionally, tracking this ratio over time reveals disease progression patterns.

Liver Waste Processing Tests

Bilirubin (Total and Direct)

Bilirubin is a yellow pigment produced when red blood cells break down. Specifically, the liver processes bilirubin and excretes it as bile. Therefore, bilirubin levels indicate how effectively your liver processes waste products.

Normal total bilirubin: 0.1-1.2 mg/dL Normal direct bilirubin: 0-0.3 mg/dL

Furthermore, elevated bilirubin causes jaundice—yellowing of skin and eyes. Additionally, the pattern of bilirubin elevation (direct vs. indirect) helps doctors determine whether the problem involves liver cells, bile ducts, or red blood cell destruction. Consequently, both total and direct bilirubin measurements provide valuable diagnostic information.

Additional Diagnostic Capabilities

Prothrombin Time (PT) and INR

The liver produces clotting factors essential for blood to clot properly. Therefore, prothrombin time (PT) and its standardized version (INR) measure how well your liver makes these clotting proteins. Consequently, these tests assess a critical liver function that directly affects your safety.

Normal PT: 11-13.5 seconds Normal INR: 0.8-1.1

Moreover, prolonged PT/elevated INR indicates impaired liver function, particularly in chronic liver disease or cirrhosis. Additionally, abnormal clotting tests require immediate medical attention as they increase bleeding risk significantly.

Hepatitis Screening

For comprehensive liver health screening Singapore, hepatitis B and C testing is essential. Moreover, viral hepatitis remains Singapore’s leading cause of liver cirrhosis and cancer. Therefore, everyone should know their hepatitis status.

Hepatitis B Surface Antigen (HBsAg): Indicates active hepatitis B infection Hepatitis B Surface Antibody (Anti-HBs): Indicates immunity from vaccination or past infection Hepatitis C Antibody (Anti-HCV): Screens for hepatitis C exposure

Imaging and Advanced Tests

For patients with abnormal liver function tests or specific risk factors, HOP can coordinate additional testing. Furthermore, these advanced tests provide detailed assessment when blood tests alone aren’t sufficient.

• Liver ultrasound: Visualizes liver structure, detects fatty liver, tumors, or bile duct problems. Moreover, ultrasound is non-invasive and painless.
• FibroScan: Non-invasive assessment of liver stiffness (fibrosis/cirrhosis). Additionally, this technology quantifies scarring without biopsy.
• AFP (Alpha-fetoprotein): Tumor marker for liver cancer screening. Consequently, regular AFP monitoring saves lives through early cancer detection.

Comprehensive Medical Review

Doctor Consultation Included

Importantly, all HOP health screening packages include a comprehensive doctor consultation at no additional charge. Moreover, this consultation ensures you fully understand your results and receive personalized guidance. During this consultation, your doctor will:

• Review all liver function test results in detail
• Explain what the findings mean for your liver health
• Assess your overall risk profile based on test results and medical history
• Recommend lifestyle modifications if needed
• Discuss whether medications or specialist referral is appropriate
• Determine if additional testing (imaging, FibroScan, liver biopsy) is necessary

If your screening reveals findings requiring further investigation, your HOP doctor will provide appropriate referrals to hepatology specialists who can perform more advanced diagnostic procedures. Therefore, seamless care coordination is always ensured.

Who Needs Liver Health Screening Singapore?

While liver screening benefits everyone eventually, certain groups should prioritize getting screened sooner and more frequently. Indeed, understanding your risk profile helps determine when to start screening.

High-Risk Groups Requiring Screening

Have obesity or are overweight: With 40% of Singaporeans having fatty liver disease and obesity being the primary driver, all overweight individuals should undergo liver screening. Consequently, even “normal weight” people with abdominal obesity need screening.

Have diabetes or pre-diabetes: Diabetics face more than double the risk of developing liver cancer, even without viral hepatitis. Therefore, comprehensive liver health screening is essential for all diabetic patients. Moreover, pre-diabetics should also start monitoring liver function early.

Have high cholesterol or triglycerides: Dyslipidemia directly contributes to fatty liver development. Moreover, people with metabolic syndrome (combination of obesity, diabetes, hypertension, and high cholesterol) face particularly high liver disease risk. Consequently, regular screening becomes critical.

Consume alcohol regularly: Any regular alcohol consumption warrants liver monitoring. Furthermore, even moderate drinking (2-3 drinks several times weekly) can cause liver damage in susceptible individuals. Additionally, binge drinking significantly accelerates liver disease progression. Therefore, drinkers should prioritize annual screening.

Have viral hepatitis B or C: All hepatitis B carriers require regular liver function monitoring and liver cancer screening. Moreover, even people successfully treated for hepatitis C should continue periodic screening, as liver damage may persist. Consequently, lifelong monitoring is essential.

Have a family history of liver disease: If relatives developed liver cancer, cirrhosis, or chronic hepatitis, start screening earlier. Additionally, some genetic liver conditions like hemochromatosis run in families. Therefore, family history significantly increases screening importance.

Additional Screening Indicators

Take medications long-term: Certain medications require periodic liver monitoring. Therefore, people on methotrexate, some antibiotics, certain seizure medications, or long-term NSAIDs should undergo regular liver screening. Specifically, medication-induced liver injury can be subtle and progressive.

Experience unexplained symptoms: Fatigue, abdominal discomfort, nausea, or changes in appetite sometimes signal liver problems, though early liver disease usually causes no symptoms. However, any persistent unexplained symptoms warrant investigation.

Have abnormal liver test results previously: If past screening showed mildly elevated liver enzymes, follow-up testing is essential to monitor for progression. Moreover, even mildly elevated results can indicate developing liver disease.

Are of Southeast Asian descent: Singapore’s high hepatitis B prevalence and genetic factors increase baseline liver disease risk for local populations. Consequently, ethnicity plays a role in screening recommendations.

Work in high-stress environments: Corporate wellness increasingly recognizes liver disease prevention’s importance. Moreover, HOP Medical Centre’s Corporate Health Screening programs bring comprehensive liver assessments directly to your workplace. Therefore, busy professionals can prioritize their liver health conveniently.

Recommended Screening Frequency

Screening frequency depends on your individual risk profile:

• Low risk (no risk factors, normal weight, no alcohol): Every 2-3 years as part of general health screening
• Moderate risk (one major risk factor like obesity or moderate alcohol use): Annually
• High risk (diabetes, hepatitis B/C, multiple risk factors): Every 6-12 months
• Known liver disease: Every 3-6 months depending on severity and treatment response

According to Singapore medical guidelines, individuals with hepatitis B should undergo liver cancer screening (AFP blood test and ultrasound) every 6 months, while those with cirrhosis require even more frequent monitoring. Moreover, early detection through regular screening significantly improves long-term outcomes. Therefore, adhering to recommended screening intervals is crucial for liver health preservation.

What to Expect at HOP Medical Centre

Understanding HOP’s screening process helps you prepare for your visit and know what to expect. Moreover, our streamlined approach ensures minimal disruption to your busy schedule.

Before Your Screening

Preparing for your appointment:

• Fasting: Most liver function tests don’t strictly require fasting. However, for most accurate results, an 8-12 hour fast (plain water permitted) is recommended. Check with HOP when booking. Moreover, fasting helps ensure consistent baseline measurements.
• Medication list: Bring information about current medications, including supplements and herbal remedies, as these can affect liver tests. Additionally, inform staff about any recent medication changes.
• Alcohol avoidance: Avoid alcohol for 24-48 hours before testing. Furthermore, alcohol can temporarily elevate liver enzymes and skew results.
• Medical history: Be prepared to discuss symptoms, family history of liver disease, alcohol consumption patterns, and potential exposures. Moreover, honest disclosure helps doctors interpret results accurately.
• Location: Choose between our convenient Orchard (Palais Renaissance) or Tampines (CPF Building) locations. Additionally, both facilities offer identical high-quality services.

During Your Screening at HOP

Comprehensive liver health screening at HOP Medical Centre typically takes 30 minutes to 1 hour for basic packages, or up to 2 hours for executive packages with imaging. Moreover, our efficient process ensures you’re never kept waiting unnecessarily.

The HOP screening process:

1. Streamlined check-in: Quick registration at our modern facilities with minimal waiting time. Indeed, most patients complete check-in within 5 minutes.
2. Medical history review: A healthcare coordinator discusses your health background, risk factors, and liver disease concerns. Furthermore, this helps personalize your screening experience.
3. Vital signs assessment: Blood pressure, pulse, weight, height, and BMI measurements—all relevant to liver disease risk. Additionally, these baseline measurements help doctors interpret your results.
4. Blood sample collection: Our skilled phlebotomists (some with over 20,000 procedures performed) ensure a comfortable experience with a >99% first-stick success rate. Additionally, blood tests measure ALT, AST, GGT, ALP, bilirubin, albumin, total protein, and hepatitis markers. Therefore, you can expect minimal discomfort.
5. Additional tests if included: Depending on your package, may include liver ultrasound, FibroScan, AFP tumor marker, or other specialized tests. Consequently, comprehensive assessment is completed in one visit.

All testing is completed at our one-stop facilities equipped with in-house diagnostic capabilities, eliminating the need for multiple appointments at different locations.

After Your Screening: Results and Consultation

After Your Screening: Results and Consultation

HOP’s results delivery and follow-up:

• Fast results: Comprehensive reports delivered within one week (3 working days for express packages). Consequently, you won’t be left waiting anxiously for your results.
• Doctor consultation included: Every screening package includes a thorough consultation at no additional charge. Moreover, this ensures you fully understand your results.
• Clear results explanation: Easy-to-understand reports with normal ranges clearly marked. Therefore, even complex medical data becomes accessible.
• Personalized recommendations: Specific guidance based on your individual findings. Additionally, recommendations are tailored to your lifestyle and risk factors.
• Follow-up support: Specialized helpline for consultations after receiving your report. Furthermore, you’re never alone in managing your liver health.
• Specialist referrals if needed: Coordination with hepatology specialists if further evaluation is recommended. Consequently, seamless care transitions are ensured.

During your consultation, your HOP doctor will:

• Review all liver function test results in detail
• Explain what the findings mean for your liver health
• Identify any liver disease and assess severity
• Calculate your risk for liver disease progression
• Recommend lifestyle modifications to protect liver function
• Discuss whether medications or antiviral treatment is appropriate
• Determine if hepatology specialist referral or additional testing (FibroScan, liver biopsy) is necessary

Book Your Liver Health Screening at HOP

Understanding Your Liver Health Screening Results

Interpreting liver health screening Singapore results requires medical expertise, but understanding the basics helps you engage meaningfully with your healthcare provider. Moreover, knowing what the numbers mean empowers you to take action. Therefore, familiarizing yourself with these key markers is valuable.

Liver Enzyme Patterns

Hepatocellular Pattern (liver cell damage):

• ALT and AST elevated more than ALP
• Seen in viral hepatitis, fatty liver, drug-induced liver injury, autoimmune hepatitis

Cholestatic Pattern (bile flow problems):

• ALP and GGT elevated more than ALT/AST
• Seen in bile duct obstruction, primary biliary cholangitis, drug reactions

Mixed Pattern:

• Both liver enzymes (ALT/AST) and cholestatic enzymes (ALP/GGT) elevated
• Seen in various liver conditions

The R Ratio

Doctors use the R ratio to classify liver injury patterns. Furthermore, this calculation helps pinpoint the specific type of liver problem.

R = (ALT value ÷ ALT upper limit of normal) ÷ (ALP value ÷ ALP upper limit of normal)

• R > 5: Hepatocellular pattern
• R < 2: Cholestatic pattern
• R = 2-5: Mixed pattern

Consequently, the R ratio guides doctors toward the correct diagnosis and treatment approach.

AST/ALT Ratio

The AST/ALT ratio provides diagnostic clues. Moreover, this simple calculation reveals important information about liver disease causes.

• AST/ALT > 2: Suggests alcoholic liver disease
• AST/ALT < 1: Typical of viral hepatitis or fatty liver disease
• AST/ALT approximately 1: Non-specific liver damage

Therefore, doctors always calculate this ratio when interpreting liver enzyme results.

Albumin and Synthetic Function

Normal albumin: 3.5-5.5 g/dL

Low albumin suggests chronic liver disease where the liver can no longer produce adequate protein. Furthermore, albumin below 2.5 g/dL indicates severe liver dysfunction. Consequently, albumin levels help stage liver disease severity.

Bilirubin Levels

Normal total bilirubin: 0.1-1.2 mg/dL

• Mildly elevated (1.2-3.0 mg/dL): May not cause visible jaundice. However, subtle changes in skin or eye color might occur.
• Moderately elevated (3.0-10.0 mg/dL): Usually causes noticeable jaundice. Moreover, medical attention becomes urgent at this level.
• Severely elevated (>10.0 mg/dL): Indicates serious liver or bile duct problems. Consequently, immediate medical intervention is required.

Understanding Normal vs. Abnormal Results

Normal liver function tests don’t automatically rule out all liver disease. Indeed, fatty liver disease can exist with completely normal liver enzymes. Therefore, if you have risk factors (obesity, diabetes), imaging studies like ultrasound may still be warranted even with normal blood tests. Moreover, serial testing over time reveals trends that single tests cannot.

Abnormal liver function tests don’t automatically mean cirrhosis or liver failure. Indeed, mildly elevated liver enzymes often reflect reversible conditions like fatty liver disease. Furthermore, with lifestyle changes and appropriate treatment, many people can normalize their liver tests completely. Therefore, abnormal results should prompt action, not panic.

Abnormal results require investigation to determine the cause. Moreover, your HOP doctor will interpret results in the context of your overall health, risk factors, and medical history to develop an appropriate diagnostic and treatment plan. Consequently, comprehensive assessment ensures accurate diagnosis and optimal treatment.

Taking Action Based on Your Results

Liver health screening only benefits you if you act on the results. Indeed, early detection creates opportunities for intervention. Depending on what your HOP screening reveals, action steps may include lifestyle changes, medical management, and ongoing monitoring. Moreover, the sooner you act, the better your outcomes.

Lifestyle Modifications for Liver Health

For fatty liver disease or elevated liver enzymes:

• Weight loss: Even 5-10% body weight reduction can significantly improve fatty liver. Moreover, studies show 7-10% weight loss can reduce liver inflammation and may reverse early fibrosis. Therefore, weight management is crucial. Additionally, sustainable weight loss through gradual changes produces lasting results.
• Dietary changes: Reduce sugar intake (especially fructose in sodas and fruit juice), limit refined carbohydrates, increase vegetables and whole grains, choose lean proteins. Additionally, avoiding processed foods helps liver recovery. Furthermore, Mediterranean-style diets show particular benefit for liver health.
• Exercise: Aim for 150 minutes weekly of moderate-intensity activity. Furthermore, exercise reduces liver fat even without weight loss. Consequently, physical activity is essential regardless of weight changes. Moreover, combining aerobic and resistance training maximizes benefits.
• Alcohol elimination: Complete abstinence for alcoholic liver disease; moderation or avoidance for fatty liver disease. Indeed, even small amounts can impede recovery. Therefore, total abstinence is often recommended.
• Diabetes control: Maintain HbA1c below 7% to reduce liver disease progression. Moreover, good glycemic control directly protects liver cells. Consequently, managing blood sugar becomes doubly important for liver health.
• Cholesterol management: Control lipids through diet, exercise, and medication if needed. Additionally, reducing triglycerides specifically helps liver fat accumulation. Therefore, comprehensive metabolic management protects your liver.

Medical Management Options

For confirmed liver disease or high-risk patients:

• Antiviral therapy: Direct-acting antivirals can cure hepatitis C. Additionally, nucleos(t)ide analogues control hepatitis B and prevent progression to cirrhosis. Therefore, early treatment is essential. Moreover, newer medications have excellent safety profiles with minimal side effects.
• Vitamin E and pioglitazone: May benefit some patients with non-alcoholic steatohepatitis (NASH). However, these should only be used under medical supervision. Furthermore, benefits must be weighed against potential risks.
• Diabetes medications: SGLT2 inhibitors and GLP-1 agonists show promise for fatty liver disease. Moreover, these medications address both diabetes and liver fat simultaneously. Consequently, they represent exciting new treatment options.
• Ursodeoxycholic acid: For certain cholestatic liver conditions. Specifically, this helps improve bile flow. Additionally, it reduces liver inflammation in select patients.
• Medication review: Discontinue potentially hepatotoxic medications when possible. Indeed, eliminating liver-damaging drugs is crucial. Therefore, thorough medication review is essential.

Your HOP doctor will discuss appropriate treatment options during your consultation and can prescribe medications or provide referrals as needed. Furthermore, treatment plans are personalized based on your specific liver condition and overall health status. Therefore, you receive individualized care tailored to your needs.

Hepatitis Vaccination

If screening shows no hepatitis B immunity, vaccination is strongly recommended to prevent this major cause of liver disease. Moreover, the hepatitis B vaccine is safe and effective, providing lifelong protection for most people. Additionally, vaccination is particularly important for healthcare workers, people with multiple sexual partners, and those with chronic liver disease from other causes. Consequently, checking immunity status and vaccinating if needed protects your liver health long-term.

Specialist Referrals When Needed

If screening reveals concerning findings:

Your HOP doctor may refer you to hepatology specialists for further evaluation. Depending on your results, additional procedures might include advanced diagnostic testing. Moreover, HOP coordinates all referrals to ensure continuity of care.

• Liver ultrasound or CT/MRI: Detailed liver structure imaging. Furthermore, these imaging studies detect abnormalities blood tests cannot reveal.
• FibroScan (transient elastography): Non-invasive liver stiffness measurement to assess fibrosis. Additionally, this technology quantifies scarring without requiring biopsy.
• Liver biopsy: If the cause or extent of liver disease is unclear. However, biopsies are now less commonly needed due to advanced non-invasive tests.
• Endoscopy: For patients with cirrhosis to check for varices (enlarged veins that can bleed). Moreover, detecting varices early enables preventive treatment.

HOP’s experienced medical team will coordinate appropriate referrals and ensure continuity of care throughout your liver health journey. Therefore, you receive seamless transitions between primary and specialist care. Additionally, your HOP doctor remains involved in monitoring your ongoing treatment.

Monitoring and Follow-Up

For all liver disease patients:

• Regular liver function monitoring: Every 3-6 months depending on condition severity. Consequently, consistent tracking allows early detection of progression.
• Liver cancer screening: For hepatitis B, cirrhosis, or advanced fibrosis—AFP blood test and ultrasound every 6 months. Indeed, early cancer detection dramatically improves survival rates.
• Fibrosis assessment: Periodic FibroScan or other non-invasive tests to monitor disease progression. Moreover, tracking fibrosis helps guide treatment decisions.
• Nutrition counseling: Specialized dietary guidance for liver disease. Additionally, proper nutrition supports liver recovery and function.
• Vaccination status: Ensure vaccination against hepatitis A and B. Furthermore, preventing additional viral hepatitis is crucial for liver protection.

Early detection and consistent management can prevent progression to cirrhosis and liver cancer, significantly improving long-term outcomes. Therefore, adhering to recommended follow-up schedules is essential for optimal liver health.

Why Choose HOP Medical Centre for Liver Health Screening Singapore

At HOP Medical Centre, we understand that liver health screening represents an investment in your future quality of life. Furthermore, with over 20 years of specialized expertise serving Singapore, we’ve conducted more than 800,000 health screenings and helped 45,000+ patients annually maintain optimal liver health. Consequently, our experience and track record speak for themselves. Moreover, we combine cutting-edge diagnostic capabilities with personalized medical care.

Comprehensive In-House Diagnostic Capabilities

Our complete liver health screening includes:

Complete In-House Diagnostic Capabilities

• Comprehensive liver enzyme panel: ALT, AST, ALP, GGT. Additionally, all tests use the latest analytical methods for accuracy.
• Liver synthetic function tests: Albumin, total protein, prothrombin time. Moreover, these assess your liver’s production capabilities.
• Bilirubin testing: Total and direct bilirubin. Therefore, bile processing function is thoroughly evaluated.
• Hepatitis screening: Hepatitis B and C testing available. Furthermore, early viral detection enables timely treatment.
• Additional markers: Glucose, HbA1c, lipid panel relevant to liver disease risk. Consequently, comprehensive metabolic assessment is included.
• Coordination with imaging: Ultrasound services when needed. Moreover, seamless referrals ensure efficient diagnostic workflows.

Expert Medical Team and Quality Assurance

Expert Medical Team

• Experienced phlebotomists: Some with over 20,000 procedures performed, achieving >99% first-stick success rate. Consequently, you experience minimal discomfort during blood collection.
• Skilled medical professionals: Trained in liver disease risk assessment and management. Moreover, continuous professional development ensures cutting-edge expertise.
• Doctor consultation included: Every screening includes personalized review of results at no additional charge. Therefore, you receive comprehensive medical guidance automatically.

Efficient and Convenient Service

Efficient, Streamlined Process

• Fast screening: Most liver health assessments completed in 30 minutes to 1 hour. Additionally, efficient workflows minimize your time commitment.
• Rapid results: Comprehensive reports delivered within 3-7 working days. Moreover, urgent findings are communicated immediately.
• Minimal waiting time: Efficient scheduling and dedicated facilities. Consequently, your valuable time is respected.
• One-stop convenience: All testing completed at a single location. Furthermore, no need for multiple appointments at different facilities.

Convenient Locations

• Orchard (Palais Renaissance): 390 Orchard Road, #11-03/04, Singapore 238871
• Tampines (CPF Building): 1 Tampines Central 5, #07-04/05, Singapore 529508

Comprehensive Post-Screening Support

Post-Screening Support

• Comprehensive consultation: Detailed explanation of liver function results and liver disease assessment. Moreover, doctors take time to answer all your questions.
• Specialized helpline: Available for questions after receiving your report. Additionally, follow-up concerns are addressed promptly.
• Follow-up coordination: Specialist referrals if hepatology evaluation is needed. Furthermore, referrals are expedited for urgent cases.
• Treatment guidance: Clear recommendations for lifestyle modifications or medical management. Therefore, you know exactly what steps to take.

Flexible Screening Options for Every Need

Flexible Screening Options

• Fasting and non-fasting packages: Flexible options to accommodate your schedule. Moreover, we work around your convenience.
• Corporate wellness programs: Mobile screening units for workplace health assessments. Additionally, group bookings receive special attention.
• Executive packages: Comprehensive screening tailored for busy professionals. Furthermore, premium service ensures efficiency.
• Express options: Quick packages for time-conscious individuals. Consequently, basic screening takes minimal time.

Whether you’re seeking preventive screening or need liver function assessment due to diabetes, obesity, alcohol use, or other risk factors, HOP provides the comprehensive liver evaluation necessary to protect your liver health through our proven track record of serving over 500 corporate clients annually. Moreover, our patient-centered approach ensures personalized care at every step. Therefore, your liver health journey is guided by experienced professionals dedicated to your wellbeing.

Schedule Your Liver Health Screening at HOP

The Bottom Line: Your Liver Deserves Attention Now

Approximately 40% of Singaporeans have fatty liver disease—significantly above the global average—yet most remain completely unaware. Moreover, with liver disease burden projected to increase from 1,492,000 to 1,799,000 cases between 2019 and 2030, the time to prioritize your liver health is now—not later, not “when symptoms appear,” but today.

Liver health screening Singapore medical centers like HOP Medical Centre offer provides the early detection necessary to prevent liver disease progression before irreversible damage occurs. Furthermore, these screenings identify problems you cannot feel—silent inflammation and fat accumulation destroying your liver while you feel perfectly healthy.

Remember: fatty liver disease is completely reversible in early stages through lifestyle changes alone—but only if you know you have it. Indeed, liver health screening gives you the information needed to take control before cirrhosis develops. Therefore, don’t wait for jaundice, abdominal swelling, or confusion—symptoms that indicate advanced liver disease.

Consequently, schedule your liver health screening Singapore at HOP Medical Centre today, and give yourself the gift of early detection and prevention.

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Frequently Asked Questions About Liver Health Screening

How much does liver health screening cost at HOP Medical Centre?

Liver health screening costs at HOP vary depending on the comprehensive nature of your chosen package. Specifically, our screening packages range from Express options starting at $52.32 to comprehensive Executive packages. Furthermore, all packages include liver function testing (ALT, AST, ALP, GGT, bilirubin, albumin), and doctor consultation at no additional charge. For specific pricing information on packages that include detailed liver function assessment and hepatitis screening, contact our Orchard or Tampines locations directly, or visit hop.sg. Additionally, we offer transparent pricing with all costs clearly outlined.

Do I need to fast before liver health screening?

For most accurate liver function test results, an 8-12 hour fast (plain water permitted) is recommended. However, some liver tests can be done without fasting. Specifically, ALT, AST, and bilirubin are generally not significantly affected by recent meals, though bilirubin is best measured fasting. Moreover, if your package includes glucose or lipid testing (both relevant to fatty liver disease), fasting is important. Consequently, HOP will provide specific preparation instructions when you book your appointment based on your selected package.

How long does liver health screening take at HOP?

At HOP Medical Centre, basic liver function screening typically takes 30 minutes to 1 hour, including blood draw and consultation. However, more comprehensive Executive packages that include additional testing or imaging may require 1-2 hours. Furthermore, our efficient screening process minimizes waiting time, and all testing is completed at our single-location facility with results delivered within 3-7 working days.

What if my liver screening shows abnormal results?

Abnormal liver function results don’t automatically mean cirrhosis or liver failure. Indeed, during your included doctor consultation, our medical team will explain what the findings mean for your liver health and recommend appropriate next steps. These may include lifestyle modifications (weight loss, alcohol cessation, dietary changes), hepatitis treatment, repeat testing to confirm results, or referral to hepatology specialists for additional evaluation. Additionally, HOP provides follow-up support through our specialized helpline, and our doctors coordinate specialist referrals if needed. Furthermore, early detection through screening means liver problems can often be reversed or stabilized before they become severe.

Can fatty liver disease be reversed?

Yes, early-stage fatty liver disease is completely reversible. Indeed, research shows that 7-10% body weight loss can significantly reduce liver fat and inflammation. Moreover, with lifestyle changes including diet modification, regular exercise, diabetes control, and alcohol avoidance, many people completely normalize their liver tests within 6-12 months. However, once fatty liver progresses to cirrhosis (advanced scarring), the damage is largely irreversible, though progression can be halted. This is why liver health screening Singapore at HOP Medical Centre is so critical—catching fatty liver early while reversal is still possible.

How often should people with hepatitis B get liver screening?

All hepatitis B carriers should undergo comprehensive liver health screening every 6-12 months, including liver function tests (ALT, AST) and liver cancer screening (AFP blood test and liver ultrasound). Specifically, Singapore medical guidelines recommend AFP and ultrasound every 6 months for high-risk patients including those with cirrhosis, family history of liver cancer, or active hepatitis. Furthermore, even people with low viral loads (“inactive carriers”) require periodic monitoring, as liver cancer can develop even with minimal liver inflammation. Therefore, HOP Medical Centre’s screening packages provide comprehensive hepatitis B monitoring in convenient single-visit appointments.

What’s the difference between ALT and AST?

Both ALT and AST are liver enzymes that leak into blood when liver cells are damaged. However, ALT is more specific to the liver, while AST is also found in heart muscle, skeletal muscles, and other organs. Specifically, ALT elevation more reliably indicates liver-specific problems. Moreover, the AST/ALT ratio provides diagnostic clues—a ratio greater than 2:1 suggests alcoholic liver disease, while a ratio less than 1 is typical of viral hepatitis or fatty liver disease. Consequently, your doctor interprets both enzymes together, along with other tests, to assess your liver health comprehensively.

Where can I get liver health screening in Singapore?

HOP Medical Centre operates two convenient locations in Singapore:

• Orchard: Palais Renaissance, 390 Orchard Road, #11-03/04, Singapore 238871
• Tampines: CPF Building, 1 Tampines Central 5, #07-04/05, Singapore 529508

Furthermore, both facilities are equipped with complete in-house diagnostic capabilities including comprehensive liver function blood testing and coordination with imaging services when needed. Additionally, we can complete liver health screening in a single visit with results delivered within 3-7 working days and doctor consultation included.

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References:

1. Muthiah, M., & Lim, S.G. (2018). Liver Disease in Singapore. Euroasian Journal of Hepato-Gastroenterology, 8(1), 66-68. https://doi.org/10.5005/jp-journals-10018-1262
2. Tan, H.J., Yudhistira, A., Lim, J.K., et al. (2021). Public awareness and knowledge of liver health and diseases in Singapore. Journal of Gastroenterology and Hepatology, 36(9), 2577-2584. https://doi.org/10.1111/jgh.15496
3. Singapore Ministry of Health. (2010). National Health Survey 2010. Singapore.
4. Ng, Q.X. (2024). 2024 Is A Historic Year for Fatty Liver Disease. What’s Next? Biotech Connection Singapore. Retrieved from https://www.biotechconnection-sg.org/2024-historic-year-fatty-liver-disease/
5. Teng, M.L.P., Ng, C.H., Huang, D.Q., et al. (2023). Global incidence and prevalence of nonalcoholic fatty liver disease. Clinical and Molecular Hepatology, 29(Suppl), S32-S42. https://doi.org/10.3350/cmh.2022.0365
6. Ng, C.H., Lim, W.H., Lim, G.E.H., et al. (2022). Non-alcoholic fatty liver disease screening in type 2 diabetes mellitus: A cost-effectiveness and price threshold analysis. Annals Academy of Medicine Singapore, 51(11), 680-689.
7. Goh, G.B., Pagadala, M.R., Dasarathy, J., et al. (2016). Perceptions of non-alcoholic fatty liver disease – an Asian community-based study. Gastroenterology Report, 4(2), 131-136. https://doi.org/10.1093/gastro/gov047
8. Giannini, E.G., Testa, R., & Savarino, V. (2005). Liver enzyme alteration: a guide for clinicians. Canadian Medical Association Journal, 172(3), 367-379. https://doi.org/10.1503/cmaj.1040752

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Image Metadata:

Featured Image:

• Title: Liver Health Screening Singapore – Liver Function Testing
• Alt text: Medical professional conducting liver health screening blood test Singapore
• Caption: Comprehensive liver health screening Singapore at HOP Medical Centre for early detection
• Description: Medical professional preparing blood test for liver function screening at HOP Medical Centre Singapore, including ALT, AST, GGT, bilirubin, and albumin testing for early detection of fatty liver disease, hepatitis, and liver damage.